Amid growing concern over drug-resistant superbugs and nonhealing wounds that endanger diabetes patients, nature’s original antibiotic—honey—is making a comeback.

More than 4,000 years after Egyptians began applying honey to wounds, Derma Sciences Inc., a New Jersey company that makes medicated and other advanced wound care products, began selling the first honey-based dressing this fall after it was approved by the U.S. Food and Drug Administration.

Called Medihoney, it is made from a highly absorbent seaweed-based material, saturated with manuka honey, a particularly potent type that experts say kills germs and speeds healing. Also called Leptospermum honey, manuka honey comes from hives of bees that collect nectar from manuka and jelly bushes in Australia and New Zealand.

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